Caveolae and propofol effects on airway smooth muscle

BACKGROUND: The i.v. anaesthetic propofol produces bronchodilatation. Airway relaxation involves reduced intracellular Ca(2+) ([Ca(2+)](i)) in airway smooth muscle (ASM) and lipid rafts (caveolae), and constitutional caveolin proteins regulate [Ca(2+)](i). We postulated that propofol-induced broncho...

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Main Authors: Grim, K. J., Abcejo, A. J., Barnes, A., Sathish, V., Smelter, D. F., Ford, G. C., Thompson, M. A., Prakash, Y. S., Pabelick, C. M.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
主題:
Respiration and the Airway
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415286/
https://ncbi.nlm.nih.gov/pubmed/22542538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aes130
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