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Pre-clinical toxicity assessment of tumor-targeted interleukin-12 low-intensity electrogenetherapy
This study’s goal was to assess the safety of tumor-targeted interleukin-12 (ttIL-12) when administered by electrogenetherapy in C3H/HeJ mice by identifying an initial safe dose for human dose escalation schemes, toxicity target organs, markers of toxicity, and toxicity reversibility. Tumor-free mic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415231/ https://ncbi.nlm.nih.gov/pubmed/21233859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.77 |
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