Binding of β-Amyloid (1–42) Peptide to Negatively Charged Phospholipid Membranes in the Liquid-Ordered State: Modeling and Experimental Studies

To explore the initial stages of amyloid β peptide (Aβ42) deposition on membranes, we have studied the interaction of Aβ42 in the monomeric form with lipid monolayers and with bilayers in either the liquid-disordered or the liquid-ordered (L(o)) state, containing negatively charged phospholipids. Mo...

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Detalhes bibliográficos
Main Authors: Ahyayauch, Hasna, Raab, Michal, Busto, Jon V., Andraka, Nagore, Arrondo, José-Luis R., Masserini, Massimo, Tvaroska, Igor, Goñi, Félix M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Membrane
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414892/
https://ncbi.nlm.nih.gov/pubmed/22947861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.043
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