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Binding of Congo Red to Amyloid Protofibrils of the Alzheimer Aβ(9–40) Peptide Probed by Molecular Dynamics Simulations
Congo red (CR) is a commonly used histological amyloid dye and a weak amyloid inhibitor. There is currently no experimentally available structure of CR bound to an amyloid fibril and the binding modes, and the mechanisms governing its inhibitory and optical properties are poorly understood. In this...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414877/ https://ncbi.nlm.nih.gov/pubmed/22947871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.008 |
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