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Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening
Yeast RNA polymerase (Pol) II general factor TFIIE and the TFIIH subunit Ssl2/XPB function in transition of the preinitiation complex (PIC) to the open complex. We find that the three TFIIE winged helix (WH) domains form a heterodimer, with the Tfa1/TFIIEα WH binding the Pol II clamp and the Tfa2/TF...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414687/ https://ncbi.nlm.nih.gov/pubmed/22751016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2334 |
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