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Grape Proanthocyanidin Inhibit Pancreatic Cancer Cell Growth In Vitro and In Vivo through Induction of Apoptosis and by Targeting the PI3K/Akt Pathway

Pancreatic cancer is an aggressive malignancy that is frequently diagnosed at an advanced stage with poor prognosis. Here, we report the chemotherapeutic effects of bioactive proanthocyanidins from grape seeds (GSPs) as assessed using In Vitro and In Vivo models. Treatment of human pancreatic cancer...

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Bibliografische gegevens
Hoofdauteurs: Prasad, Ram, Vaid, Mudit, Katiyar, Santosh K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414463/
https://ncbi.nlm.nih.gov/pubmed/22905202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043064
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