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Did the modulation of expression noise shape the evolution of three dimensional genome organizations in eukaryotes?

The pervasive role of distant chromatin interactions in transcriptional regulation is increasingly becoming evident. There is a possibility that the greater diversity in chromatin interactions of a genomic locus could contribute to stochastic variation in its gene expression. However, this issue has...

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Autor principal: Sandhu, Kuljeet Singh
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414405/
https://ncbi.nlm.nih.gov/pubmed/22572956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20263
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