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Srf: A key factor controlling skeletal muscle hypertrophy by enhancing the recruitment of muscle stem cells

Adult skeletal muscles adapt their fiber size to workload. We show that serum response factor (Srf) is required for satellite cell-mediated hypertrophic muscle growth. Deletion of Srf from myofibers, and not satellite cells, blunts overload-induced hypertrophy, and impairs satellite cell proliferati...

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Bibliografske podrobnosti
Main Authors: Aline, Guerci, Sotiropoulos, Athanassia
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414385/
https://ncbi.nlm.nih.gov/pubmed/22880147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioa.20699
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