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Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart

Epicardium-derived cells (EPDCs) invade the myocardium and differentiate into fibroblasts and vascular smooth muscle (SM) cells, which support the coronary vessels. The transcription factor Pod1 (Tcf21) is expressed in subpopulations of the epicardium and EPDCs in chicken and mouse embryonic hearts,...

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Hlavní autoři: Braitsch, Caitlin M., Combs, Michelle D., Quaggin, Susan E., Yutzey, Katherine E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414197/
https://ncbi.nlm.nih.gov/pubmed/22687751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.06.002
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