Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier

BACKGROUND AND PURPOSE: Nanobodies are promising antigen-binding moieties for molecular imaging and therapeutic purposes because of their favourable pharmacological and pharmacokinetic properties. However, the capability of monovalent nanobodies to reach targets in the CNS remains to be demonstrated...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Caljon, G, Caveliers, V, Lahoutte, T, Stijlemans, B, Ghassabeh, GH, Van Den Abbeele, J, Smolders, I, De Baetselier, P, Michotte, Y, Muyldermans, S, Magez, S, Clinckers, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2012
Onderwerpen:
Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413867/
https://ncbi.nlm.nih.gov/pubmed/22013955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01723.x
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items