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Pharmacological modulation of GITRL/GITR system: therapeutic perspectives

Glucocorticoid-induced TNFR-related (gitr) is a gene coding for a member of the TNF receptor superfamily. GITR activation by its ligand (GITRL) influences the activity of effector and regulatory T cells, thus participating in the development of immune response against tumours and infectious agents,...

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Detalhes bibliográficos
Main Authors: Nocentini, Giuseppe, Ronchetti, Simona, Petrillo, Maria Grazia, Riccardi, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413846/
https://ncbi.nlm.nih.gov/pubmed/22029729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01753.x
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