Human Endogenous Retrovirus Expression Is Inversely Associated with Chronic Immune Activation in HIV-1 Infection

Human endogenous retroviruses (HERV) are remnants of ancestral retroviral infections integrated into the germ line, and constitute approximately 8% of the genome. Several autoimmune disorders, malignancies, and infectious diseases such as HIV-1 are associated with higher HERV expression. The degree...

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Main Authors: Ormsby, Christopher E., SenGupta, Devi, Tandon, Ravi, Deeks, Steven G., Martin, Jeffrey N., Jones, R. Brad, Ostrowski, Mario A., Garrison, Keith E., Vázquez-Pérez, Joel A., Reyes-Terán, Gustavo, Nixon, Douglas F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413683/
https://ncbi.nlm.nih.gov/pubmed/22879884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041021
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