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Evaluation of TcpF-A2-CTB Chimera and Evidence of Additive Protective Efficacy of Immunizing with TcpF and CTB in the Suckling Mouse Model of Cholera

The secreted colonization factor, TcpF, which is produced by Vibrio cholerae 01 and 0139, has generated interest as a potential protective antigen in the development of a subunit vaccine against cholera. This study evaluated immunogenicity/protective efficacy of a TcpF holotoxin-like chimera (TcpF-A...

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Detaylı Bibliyografya
Asıl Yazarlar: Price, Gregory A., Holmes, Randall K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413659/
https://ncbi.nlm.nih.gov/pubmed/22879984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042434
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