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DNase I hypersensitivity and methylation of the 5'-flanking region of the alpha 1-fetoprotein gene during developmental and glucocorticoid-induced repression of its activity in rat liver.

Three major regions of DNase I hypersensitivity (DH) were found in alpha 1-fetoprotein (AFP) chromatin of rat liver. DH site I is located at the transcription initiation site and associated with ongoing AFP transcription. DH site II is located 2.5 kb upstream from the cap site: it is developmental s...

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Bibliografiske detaljer
Main Authors: Turcotte, B, Guertin, M, Chevrette, M, LaRue, H, Bélanger, L
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC341338/
https://ncbi.nlm.nih.gov/pubmed/2433681
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