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The tumor suppressor Apc controls planar cell polarities central to gut homeostasis

The stem cells (SCs) at the bottom of intestinal crypts tightly contact niche-supporting cells and fuel the extraordinary tissue renewal of intestinal epithelia. Their fate is regulated stochastically by populational asymmetry, yet whether asymmetrical fate as a mode of SC division is relevant and w...

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Detalhes bibliográficos
Main Authors: Bellis, Julien, Duluc, Isabelle, Romagnolo, Béatrice, Perret, Christine, Faux, Maree C., Dujardin, Denis, Formstone, Caroline, Lightowler, Sally, Ramsay, Robert G., Freund, Jean-Noël, De Mey, Jan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413367/
https://ncbi.nlm.nih.gov/pubmed/22851318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201204086
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