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Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel

[Image: see text] The TRPV4 calcium-permeable cation channel plays important physiological roles in osmosensation, mechanosensation, cell barrier formation, and bone homeostasis. Recent studies reported that mutations in TRPV4, including some in its ankyrin repeat domain (ARD), are associated with h...

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書誌詳細
主要な著者: Inada, Hitoshi, Procko, Erik, Sotomayor, Marcos, Gaudet, Rachelle
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2012
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413242/
https://ncbi.nlm.nih.gov/pubmed/22702953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300279b
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