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A twist in the tail: SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication

The RNA structure and long-range interactions of the SL9266 cis-acting replication element located within the NS5B coding region of hepatitis C virus (HCV) were determined using selective 2′-hydroxyl acylation analysed by primer extension. Marked differences were found in the long-range interactions...

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Detalhes bibliográficos
Main Authors: Tuplin, Andrew, Struthers, Madeleine, Simmonds, Peter, Evans, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413155/
https://ncbi.nlm.nih.gov/pubmed/22561372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks370
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