Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells

MicroRNAs are master gene regulators that can also be under the control of transcriptional regulation. We have previously shown that miR-145 is a tumor suppressor capable of silencing c-Myc and the tumor suppressor p53 induces miR-145 by directly binding to the miR-145 promoter, demonstrating the ro...

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Bibliographic Details
Main Authors: Sachdeva, Mohit, Liu, Qian, Cao, Julia, Lu, Zhaohui, Mo, Yin-Yuan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413133/
https://ncbi.nlm.nih.gov/pubmed/22495929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks324
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