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p53 represses c-Myc through induction of the tumor suppressor miR-145
The tumor suppressor p53 negatively regulates a number of genes, including the proto-oncogene c-Myc, in addition to activating many other genes. One mechanism of the p53-mediated c-Myc repression may involve transcriptional regulation. However, it is not clear whether microRNAs (miRNAs) play a role...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651330/ https://ncbi.nlm.nih.gov/pubmed/19202062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808042106 |
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