Identification of Stage-Specific Gene Expression Signatures in Response to Retinoic Acid during the Neural Differentiation of Mouse Embryonic Stem Cells

We have previously established a protocol for the neural differentiation of mouse embryonic stem cells (mESCs) as an efficient tool to evaluate the neurodevelopmental toxicity of environmental chemicals. Here, we described a multivariate bioinformatic approach to identify the stage-specific gene set...

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Hlavní autoři: Akanuma, Hiromi, Qin, Xian-Yang, Nagano, Reiko, Win-Shwe, Tin-Tin, Imanishi, Satoshi, Zaha, Hiroko, Yoshinaga, Jun, Fukuda, Tomokazu, Ohsako, Seiichiroh, Sone, Hideko
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2012
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413097/
https://ncbi.nlm.nih.gov/pubmed/22891073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00141
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