Quantitative Analysis of Energy Metabolic Pathways in MCF-7 Breast Cancer Cells by Selected Reaction Monitoring Assay

To investigate the quantitative response of energy metabolic pathways in human MCF-7 breast cancer cells to hypoxia, glucose deprivation, and estradiol stimulation, we developed a targeted proteomics assay for accurate quantification of protein expression in glycolysis/gluconeogenesis, TCA cycle, an...

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Bibliographic Details
Main Authors: Drabovich, Andrei P., Pavlou, Maria P., Dimitromanolakis, Apostolos, Diamandis, Eleftherios P.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412972/
https://ncbi.nlm.nih.gov/pubmed/22535206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.015214
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