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Autonomous Transmembrane Segment S4 of the Voltage Sensor Domain Partitions into the Lipid Membrane
The S4 transmembrane segment in voltage-gated ion channels, a highly basic α helix, responds to changes in membrane potential and induces channel opening. Earlier work by others indicates that the S4 segment interacts with lipids in plasma membrane, but its mechanism is unclear. Working with synthet...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412939/ https://ncbi.nlm.nih.gov/pubmed/22465069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.03.011 |
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