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The development, distribution and density of the PMCA2 calcium pump in rat cochlear hair cells

Calcium is tightly regulated in cochlear outer hair cells (OHCs). It enters mainly via mechanotransducer (MT) channels and is extruded by the PMCA2 isoform of the plasma membrane calcium ATPase, mutations in which cause hearing loss. To assess how pump expression matches the demands of Ca(2+) homeos...

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Autors principals: Chen, Qingguo, Mahendrasingam, Shanthini, Tickle, Jacqueline A., Hackney, Carole M., Furness, David N., Fettiplace, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412916/
https://ncbi.nlm.nih.gov/pubmed/22672315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2012.08159.x
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