Estimating sample sizes for pre-dementia Alzheimer’s trials based on the Alzheimer’s Disease Neuroimaging Initiative

This study modeled predementia Alzheimer’s disease (AD) clinical trials. Longitudinal data from cognitively normal (CN) and mild cognitive impairment (MCI) participants in the AD Neuroimaging Initiative were used to calculate sample size requirements for trials using outcome measures including: the...

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Main Authors: Grill, Joshua D., Di, Lijie, Lu, Po H., Lee, Cathy, Ringman, John, Apostolova, Liana G., Chow, Nicole, Kohannim, Omid, Cummings, Jeffrey L., Thompson, Paul M., Elashoff, David
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412892/
https://ncbi.nlm.nih.gov/pubmed/22503160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.03.006
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