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Persistent inflammation increases GABA-induced depolarization of rat cutaneous dorsal root ganglion neurons in vitro

Persistent inflammation is associated with a shift in spinal GABA(A) signaling from inhibition to excitation such that GABA(A)-receptor activation contributes to inflammatory hyperalgesia. We tested the hypothesis that the primary afferent is the site of the persistent inflammation-induced shift in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Yi, Lu, Shaogang, Gold, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412885/
https://ncbi.nlm.nih.gov/pubmed/22728089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.06.025
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