Therapeutic Time Window and Dose Response of Autologous Bone Marrow Mononuclear Cells for Ischemic Stroke

Although mononuclear cells (MNCs) from bone marrow are being investigated in phase I clinical trials in stroke patients, dose response, therapeutic time window and biodistribiton have not been well-characterized in animal stroke models. Long Evans rats underwent common carotid artery/middle cerebral...

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Main Authors: Yang, Bing, Strong, Roger, Sharma, Sushil, Brenneman, Miranda, Mallikarjunarao, Kasam, Xi, XiaoPei, Grotta, James C., Aronowski, Jaroslaw, Savitz, Sean I.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412881/
https://ncbi.nlm.nih.gov/pubmed/21412816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22614
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