Risk of Hormone Escape in a Human Prostate Cancer Model Depends on Therapy Modalities and Can Be Reduced by Tyrosine Kinase Inhibitors

Almost all prostate cancers respond to androgen deprivation treatment but many recur. We postulated that risk of hormone escape -frequency and delay- are influenced by hormone therapy modalities. More, hormone therapies induce crucial biological changes involving androgen receptors; some might be ta...

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Hauptverfasser: Guyader, Charlotte, Céraline, Jocelyn, Gravier, Eléonore, Morin, Aurélie, Michel, Sandrine, Erdmann, Eva, de Pinieux, Gonzague, Cabon, Florence, Bergerat, Jean-Pierre, Poupon, Marie-France, Oudard, Stéphane
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412862/
https://ncbi.nlm.nih.gov/pubmed/22879924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042252
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