Effects of Pregabalin on Central Sensitization in Patients with Chronic Pancreatitis in a Randomized, Controlled Trial

BACKGROUND: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input. The aim of the present study is to evaluate the effect...

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Autori principali: Bouwense, Stefan A. W., Olesen, Søren S., Drewes, Asbjørn M., Poley, Jan-Werner, van Goor, Harry, Wilder-Smith, Oliver H. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412837/
https://ncbi.nlm.nih.gov/pubmed/22879908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042096
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