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Effects of Pregabalin on Central Sensitization in Patients with Chronic Pancreatitis in a Randomized, Controlled Trial

BACKGROUND: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input. The aim of the present study is to evaluate the effect...

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Autors principals: Bouwense, Stefan A. W., Olesen, Søren S., Drewes, Asbjørn M., Poley, Jan-Werner, van Goor, Harry, Wilder-Smith, Oliver H. G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412837/
https://ncbi.nlm.nih.gov/pubmed/22879908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042096
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