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Variation of Mycobacterium tuberculosis Antigen-Specific IFN-γ and IL-17 Responses in Healthy Tuberculin Skin Test (TST)-Positive Human Subjects

OBJECTIVE: To determine the variation of IFN-γ and IL-17 responses to M. tuberculosis antigens in healthy TST+ humans. METHODS: We isolated peripheral blood mononuclear cells from 21 TST+ healthy adults, stimulated them with phytohemagglutinin (PHA), PPD, Ag85B, ESAT-6, and live M. bovis BCG, and as...

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Detalhes bibliográficos
Main Authors: Fan, Lin, Xiao, He-ping, Hu, Zhong-yi, Ernst, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412824/
https://ncbi.nlm.nih.gov/pubmed/22880090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042716
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