Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma

Cyclooxygenases (COX-1 and 2) catalyze the first step in prostanoid biosynthesis. They are implicated in homeostatic processes with an important role in inflammation and carcinogenesis. In the liver, COX-2 expression is restricted to proliferation or dedifferentiation situations. The COX-2 promoter...

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Autors principals: Fernández-Alvarez, A, Llorente-Izquierdo, C, Mayoral, R, Agra, N, Boscá, L, Casado, M, Martín-Sanz, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412654/
https://ncbi.nlm.nih.gov/pubmed/23552739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.23
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