CCR7-expressing B16 melanoma cells downregulate interferon-γ-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment

The expression of the CC chemokine receptor-7 (CCR7) by cancers, including melanoma, augments lymph node (LN) metastasis, but little is known about its role in lymphangiogenesis and anti-tumor immunity. We injected control B16 murine melanoma cells (pLNCX2-B16) and CCR7-overexpressing B16 cells (CCR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Takekoshi, T, Fang, L, Paragh, G, Hwang, S T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412639/
https://ncbi.nlm.nih.gov/pubmed/23552640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.9
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