DNA methylation: sequences flanking C-G pairs modulate the specificity of the human DNA methylase.

Synthetic single-stranded oligodeoxynucleotides of known sequence have been used as in vitro substrates for a partially purified HeLa cell DNA methylase. Although most oligonucleotides tested cannot be used by the HeLa DNA methylase in vitro, we have found a unique 27mer, containing 2 C-G pairs, tha...

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Bibliografiske detaljer
Main Authors: Bolden, A H, Nalin, C M, Ward, C A, Poonian, M S, McComas, W W, Weissbach, A
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC341254/
https://ncbi.nlm.nih.gov/pubmed/4011433
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