Mixed Vector Immunization With Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity

Substantial protection can be provided against the pre-erythrocytic stages of malaria by vaccination first with an adenoviral and then with an modified vaccinia virus Ankara (MVA) poxviral vector encoding the same ME.TRAP transgene. We investigated whether the two vaccine components adenovirus (Ad)...

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Detalhes bibliográficos
Main Authors: Reyes-Sandoval, Arturo, Rollier, Christine S, Milicic, Anita, Bauza, Karolis, Cottingham, Matthew G, Tang, Choon-Kit, Dicks, Matthew D, Wang, Dong, Longley, Rhea J, Wyllie, David H, Hill, Adrian VS
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412496/
https://ncbi.nlm.nih.gov/pubmed/22354374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.25
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