Suprachoroidal Electrotransfer: A Nonviral Gene Delivery Method to Transfect the Choroid and the Retina Without Detaching the Retina

Photoreceptors and retinal pigment epithelial cells (RPE) targeting remains challenging in ocular gene therapy. Viral gene transfer, the only method having reached clinical evaluation, still raises safety concerns when administered via subretinal injections. We have developed a novel transfection me...

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Autori principali: Touchard, Elodie, Berdugo, Marianne, Bigey, Pascal, El Sanharawi, Mohamed, Savoldelli, Michèle, Naud, Marie-Christine, Jeanny, Jean-Claude, Behar-Cohen, Francine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412485/
https://ncbi.nlm.nih.gov/pubmed/22252448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.304
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