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Isolation and characterization of erlotinib-resistant human non-small cell lung cancer A549 cells

Erlotinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is an effective therapy for non-small cell lung cancer (NSCLC). However, resistance to erlotinib reduces its efficacy. To investigate the basis of erlotinib resistance, we isolated erlotinib-resistant human NSCLC A549 c...

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Detalhes bibliográficos
Main Authors: IKEDA, RYUJI, VERMEULEN, LEE C., LAU, ELIM, JIANG, ZHISHENG, KAVANAUGH, SHANNON M., YAMADA, KATSUSHI, KOLESAR, JILL M.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412472/
https://ncbi.nlm.nih.gov/pubmed/22870135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2010.198
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