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A Unique Role of RGS9-2 in the Striatum as a Positive or Negative Regulator of Opiate Analgesia

The signaling molecule RGS9-2 is a potent modulator of G-protein-coupled receptor function in striatum. Our earlier work revealed a critical role for RGS9-2 in the actions of the μ-opioid receptor (MOR) agonist morphine. In this study, we demonstrate that RGS9-2 may act as a positive or negative mod...

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Detalles Bibliográficos
Main Authors: Psigfogeorgou, Kassi, Terzi, Dimitra, Papachatzaki, Maria Martha, Varidaki, Artemis, Ferguson, Deveroux, Gold, Stephen J., Zachariou, Venetia
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412365/
https://ncbi.nlm.nih.gov/pubmed/21490202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4146-10.2011
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