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Sample Pre-Fractionation for Mass Spectrometry Quantification of Low-Abundance Membrane Proteins
Use of stable isotope-labeled full-length proteins as an internal standard prior to multiple reaction monitoring (MRM) analysis enables pre-fractionation of the target proteins and quantification of those low-abundance proteins, which cannot be reached without biological sample enrichment. In terms...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412265/ https://ncbi.nlm.nih.gov/pubmed/22607469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300587v |
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