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Lessons of leprosy: The emergence of TH17 cytokines during type II reactions (ENL) is teaching us about T-cell plasticity
BACKGROUND: Leprosy was the first disease classified according to the thymus derived T-cell in the 1960s and the first disease classified by the cytokine profile as intact interferon-γ (IFNγ) and interleukin-2 (IL2) or TH1 (tuberculoid) and deficient IFNγ and IL2 or TH2 (lepromatous), in the 1980s....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412264/ https://ncbi.nlm.nih.gov/pubmed/22527432 |
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