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Akt and mTOR in B Cell Activation and Differentiation
Activation of phosphoinositide 3-kinase (PI3K) is required for B cell proliferation and survival. PI3K signaling also controls key aspects of B cell differentiation. Upon engagement of the B cell receptor (BCR), PI3K activation promotes Ca(2+) mobilization and activation of NFκB-dependent transcript...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412259/ https://ncbi.nlm.nih.gov/pubmed/22888331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00228 |
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