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Clinical Safety, Pharmacokinetics, and Efficacy of Ambrisentan Therapy in Children With Pulmonary Arterial Hypertension

Recent trials in adult PAH revealed the efficacy of ambrisentan. However, in children with PAH, the clinical safety and pharmacokinetics of ambrisentan has not been well studied. Our aim was to investigate the clinical safety, pharmacokinetics, tolerability, and efficacy of endothelin receptor antag...

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Bibliographic Details
Main Authors: Takatsuki, Shinichi, Rosenzweig, Erika B., Zuckerman, Warren, Brady, Daniela, Calderbank, Michelle, Ivy, D. Dunbar
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412194/
https://ncbi.nlm.nih.gov/pubmed/22511577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.22555
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