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Clinical Safety, Pharmacokinetics, and Efficacy of Ambrisentan Therapy in Children With Pulmonary Arterial Hypertension

Recent trials in adult PAH revealed the efficacy of ambrisentan. However, in children with PAH, the clinical safety and pharmacokinetics of ambrisentan has not been well studied. Our aim was to investigate the clinical safety, pharmacokinetics, tolerability, and efficacy of endothelin receptor antag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takatsuki, Shinichi, Rosenzweig, Erika B., Zuckerman, Warren, Brady, Daniela, Calderbank, Michelle, Ivy, D. Dunbar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412194/
https://ncbi.nlm.nih.gov/pubmed/22511577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.22555
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