Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia

The cardiac electrical impulse depends on an orchestrated interplay of transmembrane ionic currents in myocardial cells. Two critical ionic current mechanisms are the inwardly rectifying potassium current (I(K1)), which is important for maintenance of the cell resting membrane potential, and the sod...

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Bibliographische Detailangaben
Hauptverfasser: Milstein, Michelle L., Musa, Hassan, Balbuena, Daniela Ponce, Anumonwo, Justus M. B., Auerbach, David S., Furspan, Philip B., Hou, Luqia, Hu, Bin, Schumacher, Sarah M., Vaidyanathan, Ravi, Martens, Jeffrey R., Jalife, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412015/
https://ncbi.nlm.nih.gov/pubmed/22509027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109370109
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