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Nanoparticle-based artificial RNA silencing machinery for antiviral therapy
RNA interference is a fundamental gene regulatory mechanism that is mediated by the RNA-induced silencing complex (RISC). Here we report that an artificial nanoparticle complex can effectively mimic the function of the cellular RISC machinery for inducing target RNA cleavage. Our results show that a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412013/ https://ncbi.nlm.nih.gov/pubmed/22802676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207766109 |
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