Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes

Mammalian pigmentation is driven by the intercellular transfer of pigment-containing melanosomes from the tips of melanocyte dendrites to surrounding keratinocytes. Tip accumulation of melanosomes requires myosin Va, because melanosomes concentrate in the center of melanocytes from myosin Va-null (d...

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Bibliographic Details
Main Authors: Wu, Xufeng S., Masedunskas, Andreas, Weigert, Roberto, Copeland, Neal G., Jenkins, Nancy A., Hammer, John A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412008/
https://ncbi.nlm.nih.gov/pubmed/22753477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209397109
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