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Modeling an autism risk factor in mice leads to permanent immune dysregulation

Increasing evidence highlights a role for the immune system in the pathogenesis of autism spectrum disorder (ASD), as immune dysregulation is observed in the brain, periphery, and gastrointestinal tract of ASD individuals. Furthermore, maternal infection (maternal immune activation, MIA) is a risk f...

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Main Authors: Hsiao, Elaine Y., McBride, Sara W., Chow, Janet, Mazmanian, Sarkis K., Patterson, Paul H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411999/
https://ncbi.nlm.nih.gov/pubmed/22802640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202556109
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