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IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells
To protect the organism against autoimmunity, self-reactive effector/memory T cells (T(E/M)) are controlled by cell-intrinsic and -extrinsic regulatory mechanisms. However, how some T(E/M) cells escape regulation and cause autoimmune disease is currently not understood. Here we show that blocking IL...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411948/ https://ncbi.nlm.nih.gov/pubmed/22733744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203692109 |
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