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Dopamine receptor D(3) regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI

Macromolecules enter cells by endocytosis and are sorted to different cellular destinations in early/sorting endosomes. The mechanism and regulation of sorting are poorly understood, although transitions between vesicular and tubular endosomes are important. We found that the antihypertensive drug P...

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Detalhes bibliográficos
Main Authors: Zhang, Xin, Wang, Wenchao, Bedigian, Anne V., Coughlin, Margaret L., Mitchison, Timothy J., Eggert, Ulrike S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411939/
https://ncbi.nlm.nih.gov/pubmed/22802617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207821109
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