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Crystal structure of the human spastin AAA domain
Hereditary spastic paraplegia (HSP) is a motor neuron disease caused by a progressive degeneration of the motor axons of the corticospinal tract. Point mutations or exon deletions in the microtubule-severing ATPase, spastin, are responsible for approximately 40% of cases of autosomal dominant HSP. H...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411929/ https://ncbi.nlm.nih.gov/pubmed/22446388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.03.002 |
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