Attenuation of Acute GvHD in the Absence of the Transcription Factor RORγt

Graft-versus-host disease (GvHD) remains the most significant complication after allogeneic stem cell transplantation (allo-SCT). Previously, acute GvHD had been considered to be mediated predominantly by Th1 polarized T cells. Recently, investigators have identified a second pro-inflammatory lineag...

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Autori principali: Fulton, LeShara M, Carlson, Michael J, Coghill, James M, Ott, Laura E, West, Michelle L, Panoskaltsis-Mortari, Angela, Littman, Dan R, Blazar, Bruce R, Serody, Jonathan S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411855/
https://ncbi.nlm.nih.gov/pubmed/22778391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200858
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