Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder

BACKGROUND: Meta-analyses have identified serum levels of brain-derived neurotrophic factor (BDNF) as a potential biomarker for major depressive disorder (MDD). However, at the time, commercially available human ELISA kits are unable to distinguish between proBDNF (precursor of BDNF) and mature BDNF...

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Autores principales: Yoshida, Taisuke, Ishikawa, Masatomo, Niitsu, Tomihisa, Nakazato, Michiko, Watanabe, Hiroyuki, Shiraishi, Tetsuya, Shiina, Akihiro, Hashimoto, Tasuku, Kanahara, Nobuhisa, Hasegawa, Tadashi, Enohara, Masayo, Kimura, Atsushi, Iyo, Masaomi, Hashimoto, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411809/
https://ncbi.nlm.nih.gov/pubmed/22880079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042676
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