Impact of Sex Steroid Ablation on Viral, Tumour and Vaccine Responses in Aged Mice

Recent evidence suggests that the decline in resistance to viral infections with age occurs predominantly as a result of a gradual loss of naïve antigen-specific T cells. As such, restoration of the naïve T cell repertoire to levels seen in young healthy adults may improve defence against infection...

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Autors principals: Heng, Tracy S. P., Reiseger, Jessica J., Fletcher, Anne L., Leggatt, Graham R., White, Olivia J., Vlahos, Katerina, Frazer, Ian H., Turner, Stephen J., Boyd, Richard L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411797/
https://ncbi.nlm.nih.gov/pubmed/22880080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042677
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